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Resistance to Cocaine Addiction May Be Passed Down from Father to Son

Resistance to Cocaine Addiction May Be Passed Down from Father to Son

Research from the Perelman School of Medicine at the University of Pennsylvania and Massachusetts General Hospital (MGH) reveals that sons of male rats exposed to cocaine are resistant to the rewarding effects of the drug, suggesting that cocaine-induced changes in physiology are passed down from father to son. The findings are published in the latest edition of Nature Neuroscience.

«We know that genetic factors contribute significantly to the risk of cocaine abuse, but the potential role of epigenetic influences — how the expression of certain genes related to addiction is controlled — is sti...

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